This page contains brief information about recombinant human papillomavirus (HPV) quadrivalent vaccine and a collection of links to more information about the use of this vaccine, research results, and ongoing clinical trials.
US Brand Name(s)Gardasil
FDA ApprovedYes
FDA label information for this drug is available at DailyMed.
Use in Cancer
Recombinant human papillomavirus (HPV) quadrivalent vaccine is approved to prevent some conditions caused by certain types of HPV. The vaccine protects against four different types of HPV.
HPV vaccine prevents infection with human papillomavirus (HPV) types that are associated with cause many cancers, including the following:
cervical cancer in females
vaginal and vulvar cancers in females
anal cancer in females and males
throat cancer in females and males
penile cancer in males
In addition, HPV vaccine prevents infection with HPV types that cause genital warts in both females and males.
In the United States, about 12,000 women get cervical cancer every year, and about 4,000 women die from it. HPV vaccine can prevent most of these cases of cervical cancer.
Vaccination is not a substitute for cervical cancer screening. This vaccine does not protect against all HPV types that can cause cervical cancer. Women should still get regular Pap tests.
HPV infection usually comes from sexual contact, and most people will become infected at some point in their life. About 14 million Americans, including teens, get infected every year. Most infections will go away on their own and not cause serious problems. But thousands of women and men get cancer and other diseases from HPV.
What is HPV vaccine?
HPV vaccine is approved by the FDA and is recommended by the CDC for both males and females. It is routinely given at 11 or 12 years of age, but it may be given beginning at age 9 years through age 26 years.
Most adolescents 9 through 14 years of age should get HPV vaccine as a two-dose series with the doses separated by 6 to 12 months. People who start HPV vaccination at 15 years of age and older should get the vaccine as a three-dose series with the second dose given 1 to 2 months after the first dose and the third dose given 6 months after the first dose. There are several exceptions to these age recommendations. Your healthcare provider can give you more information.
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